Whole-transcriptome maps of HepG2 cells after exposure to cationic liposomes and controls

Cationic liposomes (CLs) are non-viral vectors that play a major role in DNA transfer and gene therapy. The cellular toxicity of CLs has been validated in HepG2 cells. To address the basis of the CLs toxicity, we performed RNA-seq analysis on untreated HepG2 cells and HepG2 cells following exposure to IC50 concentration (120μM) CLs for 24h. Examination of gene expression level in CLs treated HepG2 cells and untreated cells