Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease

NIAID Data Ecosystem2026-03-11 收录

多囊肾病病理

信号转导与转录调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE128524 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2019-11-13

Dissection of metabolic reprogramming in polycystic kidney disease reveals coordinated rewiring of bioenergetic pathways

多囊肾病病理

代谢重编程

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a genetic disorder caused by loss-of-function mutations in PKD1 or PKD2. Increased glycolysis is a prominent feature of the disease, but how it

NIAID Data Ecosystem70

Fatty acid oxidation is impaired in an orthologous mouse model of Autosomal Dominant Polycystic Kidney Disease

多囊肾病病理

脂肪酸氧化

Background The major gene mutated in autosomal dominant polycystic kidney disease was first identified over 20 years ago, yet its function remains poorly understood. We have used a systems-based appro

NIAID Data Ecosystem60

Autosomal dominant polycystic kidney disease: an overview of recent genetic and clinical advances

遗传性肾病

多囊肾病病理

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common inherited kidney disease, characterized by the progressive development of multiple kidney cysts, leading to a gradual decline in

DataCite Commons2026-05-21 更新40

Supplementary Material for: UPREGULATED ANGIOTENSIN IA RECEPTORS IN THE HYPOTHALAMIC PVN SENSITISE NEUROENDOCRINE VASOPRESSIN RELEASE AND BLOOD PRESSURE IN A RODENT MODEL OF POLYCYSTIC KIDNEY DISEASE.

多囊肾病病理

血管加压素释放调控

Introduction: Angiotensin (Ang) II signalling in the hypothalamic paraventricular nucleus (PVN) via angiotensin type-1a receptors (AT1R) regulates vasopressin release and sympathetic nerve activity -

Figshare2022-06-02 更新60

STING-Dependent Cross-Talk between Cystic Epithelium and Macrophages via IFN-λ2 Promotes Autosomal Dominant Polycystic Kidney Disease

多囊肾病病理

免疫-上皮细胞互作

STING-Dependent Cross-Talk between Cystic Epithelium and Macrophages via IFN-λ2 Promotes Autosomal Dominant Polycystic Kidney Disease

integrated proteome resources50