TRcompDB v2.1, a global reference of human tandem repeat composition and mutation rate from long-read assemblies

The following motif catalogs are provided. Including the vamos genomic catalog expanded by TRExplore v1.0 (4,413,318 loci) for GRCh38 the vamos genomic catalog for CHM13 (1,168,063 loci) the vamos genomic catalog expanded by TRExplore v1.0 (4,139,061 loci) for CHM13 the curated functional catalog for GRCh38 (78 loci) All motif catalogs are generated under the v3.1 infrastructure of the catalog construction pipeline. “oriMotifs” stands for the full motif set before efficient motif selection. “effMotifs-0.1” stands for the efficient motifs selected under q=0.1. The v3.1 catalog removed loci of low motif purities in the v3.0 catalog to avoid artifacts by structural variations. TR annotations are provided as combined vcf for 416 publicly available diploid long-read assemblies. Annotations were generated using vamos v-3.1.1. Locus-specific ANOVAs by allelic length or compositions are provided in "anova.annoLen.tsv.gz" and "anova.ed2Major.tsv.gz". Estimated locus-specific mutation rates for GRCh38 are provided in a master table with locus features (mutRate_GRCh38_masterFile.tsv.gz). Columns are explained in the txt file (mutRate_GRCh38_masterFile.txt).