Composition and differential expression of the C. phytofermentans BMC locus.

a All percent similarity values are calculated from pairwise global alignments of protein sequences generated using the algorithm of Needleman and Wunsch [45], with the exception of those for Cphy_1178, 1181, and 1182. Only a segment of these three genes was homologous to designated proteins. Percent similarity values are reported for alignment of the entire homolog with a segment of the C. phytofermentans gene product (amino acids 7–184, 1–98 and 73–161 for Cphy_1178, Cphy_1181 and Cphy1182, respectively).b Pdu (propanediol utilization) nomenclature based on that of S. enterica [37].c When significant amino acid similarity with an S. enterica protein (>35%) was not detected (n.d.), we attempted to identify the most closely related characterized homolog. References for characterized homologs are as follows: Clostridium butyricum B-12 independent glycerol dehydratase and activator [31], [32], M. jannaschii fuculose-phosphate aldolase [46], O. oeni alcohol dehydrogenase [33] and E. coli glucitol operon repressor SrlR [47].