Human-HIV1 All-to-All Inter-Species Predictions using PIPE4, SPRINT, SPPS

All-to-all prediction scores between Human and HIV1 for three independent sequence-based PPI predictors: PIPE4, SPRINT, SPPS. Each algorithm was trained on intra-species PPIs (Human-Human & HIV1-HIV1) to generate the inter-species predictions. The training samples were obtained from BioGRID. The human proteome was obtained from Uniprot (Proteome Id: UP000005640) and filtered for Reviewed/Swiss-Prot status; resulting in 20,350 proteins (7 proteins excluded due to sequence length). The HIV1 proteome was similarly obtained (Proteome Id: UP000002241); resulting in 9 proteins. All 183,087 predictions are provided for each method except SPPS for which 25 human protein sequences were excluded for having non-standard amino acids. Each file contains three columns of comma separated values representing: human-protein,hiv1-protein,score where the score column represents the likelihood of interaction for that given PPI. Files are sorted on the Human protein and then on the HIV1 protein.