Maximum likelihood estimates of population parameters.

Population parameters (median values) and 95% confidence intervals obtained from fitting the model (Eqs (3)–(6)) to estimated viral loads from the lung, trachea, or nasopharynx of mice infected with either the rSeV-luc(M-F*) virus (“M-F”) or the rSeV-luc(P-M) virus (“P-M”) at a high d/v or low d/v. The initial numbers of target cells (T(0)) and infected cells (I1(0)) were fixed to the indicated value, and the initial number of productively infected cells (I2(0)) and the initial virus (V(0)) were set to 0.