HIFα-regulated genes in small intestine epithelial cells from naïve mice

HIFα works as an important transcription factor to induce target genes mediating cell proliferation, metabolism and inflammation. To gain new insights into HIFα modulated genes, we used high-throughput sequencing to analyze potential HIFa regulated genes in small intestine epithelial cells from naive mice at steady state. RNA-seq was used to define differentially expressed genes in small intestine epithelial cells from naïve mice of HIF1α∆IEC, HIF2α∆IEC mice and littermate control mice.