Canonical Wnt/β-catenin signalling is an essential regulator of various cellular functions throughout development and adulthood. Aberrant Wnt/β-catenin signalling also contributes to various pathologi
Investigation of the physiogical functions of YAP/TAZ in vascular smooth muscle cells Total RNA was prepared using isolated mouse aortic SMC of wild-type (WT) and Sm-Yap/Taz-KO mice (KO) after 18 days
scRNA-seq was performed to investigate the differences between Reninnull cells and surrounding vascular smooth muscle cells Overall design: Cells from Ren1c-/-;Myh11-CreERT2;tdTomato;Ren1c-YFP mice we
In current study, using a lentivirus-based expression system, we observed that overexpressing HIF1A-AS1 successfully promoted apoptosis, significantly altered cell cycle distribution and greatly facil