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Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency

NIAID Data Ecosystem2026-05-10 收录

数据链接：

https://figshare.com/articles/dataset/Seed_structure_and_phosphorylation_in_the_fuzzy_coat_impact_tau_seeding_competency/28687256 数据链接链接失效反馈

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资源简介：

Tau filament structures from several forms of recombinant tau.

应用场景：

创建时间：

2025-10-18

神经退行性疾病

自噬

Chaperone-mediated autophagy (CMA) involves the selective lysosomal degradation of cytosolic proteins such as SNCA (synuclein α), a protein strongly implicated in Parkinson disease (PD) pathogenesis.

DataCite Commons2020-09-03 更新50

In vitro assembled 266/297 - 391 tau filaments with KCl (10b)

tau蛋白纤维结构

神经退行性疾病

In vitro assembled 266/297 - 391 tau filaments with KCl (10b) Descriptor: Microtubule-associated protein tau Authors: Lovestam, S, Scheres, S.H.W. Deposit date: 2022-02-10 Release date: 2022-02-23 Las

Protein Data Bank Japan2024-07-17 更新40

Supplementary Material for: Toward a Speech-Based Model of Premanifest Huntington's Disease Progression using Deep Neural Networks

神经退行性疾病

生物标志物

INTRODUCTION: Huntington’s disease (HD) is a progressive neurodegenerative disorder characterized by motor, cognitive, and psychiatric decline. The Unified Huntington’s Disease Rating Scale Total Moto

NIAID Data Ecosystem30

In vitro assembled 297-408 S396D S400D T403D S404D tau filaments (42a)

tau蛋白纤维结构

神经退行性疾病

In vitro assembled 297-408 S396D S400D T403D S404D tau filaments (42a) Descriptor: Microtubule-associated protein tau Authors: Lovestam, S, Scheres, S.H.W. Deposit date: 2021-12-17 Release date: 2022-

Protein Data Bank Japan2024-07-17 更新40

Identification of the altered transcripts in the NMF291–/– cerebellum by exon array.. Mus musculus

神经退行性疾病

基因表达分析

The U2 snRNA is a basal component of the major spliceosome, which is responsible for >90% human pre-mRNA splicing. A 5-nucleotide deletion in one of the mouse U2 snRNA genes (Rnu2-8) causes cerebellar

NIAID Data Ecosystem30

Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency

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