Single-cell transcriptional profiles of lung CD45+ immune cells from WT and Ptgs2-cKO mice
收藏NIAID Data Ecosystem2026-03-13 收录
下载链接：
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE206449
下载链接
链接失效反馈官方服务：
资源简介：
To better understand the role of the COX-2-dependent lung fibroblast program in modulating the lung immune microenvironment, we generated fibroblast-targeted Ptgs2 conditional knockout (cKO) mice by crossing Pdgfra-Cre mice with Ptgs2flox/flox mice. Then we determined how Ptgs2 deficiency in CD140a+ fibroblasts alters the lung immune microenvironment by performing single-cell RNA sequencing on lung CD45+ immune cells from WT and Ptgs2-cKO mice. Lung CD45+ immune cells from WT and Ptgs2-cKO mice were isolated by Fluorescence-activated cell sorting (FACS) and analyzed using scRNAseq.
创建时间：
2022-08-05
