The relative specific activities (RAs) and apparent catalytic constants characterizing IgGs from the CSFs and sera of different MS patients in the hydrolysis of MBP*.

*The average values measured in the case of fifteen individual MS patients as mean ±S.E; for each value of individual patients a mean of three measurements was used; the error of the determination of these values did not exceed 7–10%.**The ratios of the average values are reported.‡First, the relative specific RAs of every IgG preparation (nmole MBP/1 mg of protein/1 h) was calculated and then apparent kcat values at fixed concentration of MBP (0.5 mg/ml) were calculated (kcat = V/[IgG]).The relative specific activities (RAs) and apparent catalytic constants characterizing IgGs from the CSFs and sera of different MS patients in the hydrolysis of MBP*.