Osteochondral Tissue Chip Derived from iPSCs: Modeling OA pathologies and Testing Drugs

NIAID Data Ecosystem2026-03-11 收录

组织工程疾病模型

药物筛选平台

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE140337 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2020-01-14

Atomic Force Mechanobiology of Pluripotent Stem Cell-Derived Cardiomyocytes

细胞机械生物学

药物筛选平台

We describe a method using atomic force microscopy (AFM) to quantify the mechanobiological properties of pluripotent, stem cell-derived cardiomyocytes, including contraction force, rate, duration, and

NIAID Data Ecosystem50

DataSheet1_theLiTE™: A Screening Platform to Identify Compounds that Reinforce Tight Junctions.docx

药物筛选平台

上皮屏障

Tight junctions (TJ) are formed by transmembrane and intracellular proteins that seal the intercellular space and control selective permeability of epithelia. Integrity of the epithelial barrier is ce

NIAID Data Ecosystem40

iPSCs from patients with NBS as a model uncovering disease mechanisms and a screening platform for anti-oxidants modifying genomic stability [fibroblasts]

疾病模型构建

药物筛选平台

Nijmegen Breakage Syndrome (NBS) is a rare autosomal recessive genetic disorder, first described 1981 in Nijmegen, Holland. The characteristics of NBS include genomic instability (resulting in early o

NIAID Data Ecosystem30

Computational and Experimental Characterization of dVHL Establish a Drosophila Model of VHL Syndrome

疾病模型构建

药物筛选平台

The von Hippel-Lindau (VHL) cancer syndrome is associated with mutations in the VHL gene. The pVHL protein is involved in response to changes in oxygen availability as part of an E3-ligase that target

NIAID Data Ecosystem40

A cell-loss-free concave microwell array based size-controlled multi-cellular tumoroid generation for anti-cancer drug screening

肿瘤模型构建

药物筛选平台

The 3D multi-cellular tumoroid (MCT) model is an in vivo-like, avascular tumor model that has received much attention as a refined screening platform for drug therapies. Several types of research have

NIAID Data Ecosystem30

Osteochondral Tissue Chip Derived from iPSCs: Modeling OA pathologies and Testing Drugs

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