Ontario Neurodegenerative Disease Research Initiative (ONDRI): Foundational Study Longitudinal Data - Release 2.0

Dr. Mario Masellis, Dr. Douglas Munoz, Dr. Michael Strong, Dr. Richard Swartz, ONDRI study team | ONDRI's Foundational Study includes data from 520 people living with Alzheimer's disease, mild cognitive impairment, Parkinson's disease, amyotrophic lateral sclerosis, frontotemporal dementia, or cerebrovascular disease, along with their care partners. Detailed clinical, cognitive, genetic, gait, balance, eye tracking, retinal imaging, and neuroimaging assessments were performed that enable multi-modality within- and cross-disease analyses. Data were collected from 2014-18; then standardized, cleaned, and curated to facilitate open access and sharing.

马里奥·马斯利斯博士、道格拉斯·穆诺兹博士、迈克尔·斯特朗博士、理查德·斯瓦茨博士，ONDRI研究团队 | ONDRI的基础研究涵盖了520位患有阿尔茨海默病、轻度认知障碍、帕金森病、肌萎缩侧索硬化症、额颞叶痴呆或脑血管病的患者及其护理伙伴的数据。该研究进行了详细的临床、认知、遗传、步态、平衡、眼动追踪、视网膜成像和神经影像学评估，从而实现了多模态的疾病内和跨疾病分析。数据收集于2014-2018年，随后进行了标准化、清洗和整理，以促进开放获取和共享。