Crystal structure of EGFR 696-1022 T790M in complex with Ibrutinib
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Crystal structure of EGFR 696-1022 T790M in complex with Ibrutinib Descriptor: 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one, CHLORIDE ION, Epidermal growth factor receptor Authors: Yan, X.E, Yun, C.H. Deposit date: 2017-11-21 Release date: 2017-12-27 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation. Oncotarget, 7, 2016
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2017-11-21
