crystal structure of BRD2-BD2 in complex with purine derivative
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crystal structure of BRD2-BD2 in complex with purine derivative Descriptor: Bromodomain-containing protein 2, Doxofylline, GLYCEROL Authors: Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S, Mathur, S. Deposit date: 2021-10-25 Release date: 2023-02-01 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family. Acta Crystallogr D Struct Biol, 79, 2023
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2021-10-25
