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Compounds effective against <i>P. aeruginosa</i> in the <i>C. elegans</i> assay at doses that do not inhibit bacterial growth.

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RPW-24 induced F35E12.5::GFP expression and was effective against C. elegans infected with P. aeruginosa without inhibiting growth of the bacteria. See Figure 1A and Figure S1 for the structures of these compounds. ++ represents strong activation of F35E12.5::GFP. MIC equals minimum inhibitory concentration.

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2012-06-14
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