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Identification of resistance mechanisms to small-molecule inhibition of YAP/TEAD-regulated transcription

NIAID Data Ecosystem2026-05-02 收录

基因转录调控

TEAD蛋白功能

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE269900 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2024-10-09

疟原虫抗原

基因转录调控

The pir multigene family, found in the genomes of Plasmodium vivax, P. knowlesi and the rodent malaria species, encode variant antigens that could be targets of the immune response. Individual parasit

NIAID Data Ecosystem90

Taxi knock out Transcriptome. Drosophila melanogaster

神经遗传学

基因转录调控

Maintaining taxi homeostasis in neurons is important for maintaining the neuromuscular crosstalk and flight function in Drosophila melanogaster. Transcriptome analysis of taxi show that Adar is one of

NIAID Data Ecosystem70

The IKAROS Interaction with a Complex Including Chromatin Remodeling and Transcription Elongation Activities Is Required for Hematopoiesis

基因转录调控

造血细胞分化

IKAROS is a critical regulator of hematopoietic cell fate and its dynamic expression pattern is required for proper hematopoiesis. In collaboration with the Nucleosome Remodeling and Deacetylase (NuRD

Figshare2016-01-15 更新60

TFIIS.h, a new target of p53, regulates transcription efficiency of pro-apoptotic bax gene

癌症分子机制

基因转录调控

Investigation of whole genome gene expression level changes in human colon cancer cell lines in response to p53 activation by Inauhzin (INZ), and identification of novel p53 target genes. Part of the

NIAID Data Ecosystem70

Nanoscale Dynamics of Enhancer-Promoter Interactions during Exit from Pluripotency

染色质空间构象

基因转录调控

While compelling genetic evidence supports the role of enhancers in regulating promoter activity even over large genomic distances, it remains unclear to what extent physical proximity to promoters is

NIAID Data Ecosystem60

Identification of resistance mechanisms to small-molecule inhibition of YAP/TEAD-regulated transcription

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