Crystal structure of the PFV S217H mutant intasome bound to magnesium and the INSTI MK2048
收藏Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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Crystal structure of the PFV S217H mutant intasome bound to magnesium and the INSTI MK2048 Descriptor: (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, AMMONIUM ION, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), ... Authors: Hare, S, Cherepanov, P. Deposit date: 2010-09-23 Release date: 2010-11-17 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance. Proc.Natl.Acad.Sci.USA, 107, 2010
创建时间：
2010-09-23
