Model parameters for biochemical reactions.

a All rates for internal reactions were assumed to be the same as on the cell surface. Unit conversion was required (not shown) for kon and KD in internal compartments (from M-1s-1 to (#/cm2)-1s-1 for kon and from M to #/cm2 for KD) using the total volume of the specified endosomal compartment per unit surface area (See S2 Table- not assumed to be spherical). Note that all rates are effective rates; diffusion considerations are lumped into these effective rates. Model parameters for biochemical reactions.