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Crystal structure of the first bromodomain of human BRD4 in complex with MA2-014

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Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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Crystal structure of the first bromodomain of human BRD4 in complex with MA2-014 Descriptor: 1,2-ETHANEDIOL, 2-methyl-~{N}-[3-[[5-methyl-2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]amino]phenyl]propane-2-sulfonamide, Bromodomain-containing protein 4 Authors: Ember, S.W, Zhu, J.-Y, Schonbrunn, E. Deposit date: 2015-12-04 Release date: 2017-04-05 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Potent Dual BET Bromodomain-Kinase Inhibitors as Value-Added Multitargeted Chemical Probes and Cancer Therapeutics. Mol. Cancer Ther., 16, 2017
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2015-12-04
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