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New Approach to the Stereoselective Synthesis of Tertiary Methyl Ethers

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NIAID Data Ecosystem2026-03-06 收录
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The Lewis acid-mediated addition of titanium enolates from 1 to dimethyl ketals of aliphatic methyl ketones followed by removal of the chiral auxiliary furnishes enantiomerically pure derivatives containing a tertiary methyl ether and a contiguous stereocenter in a straightforward manner.

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2009-05-21
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