Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor
收藏Protein Data Bank Japan2023-11-08 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3w69
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Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor Descriptor: (5R,6S)-2-[((2S,5R)-2-{[(3R)-4-acetyl-3-methylpiperazin-1-yl]carbonyl}-5-ethylpyrrolidin-1-yl)carbonyl]-5,6-bis(4-chlorophenyl)-3-isopropyl-6-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazole, E3 ubiquitin-protein ligase Mdm2, SULFATE ION Authors: Shimizu, H, Katakura, S, Miyazaki, M, Naito, H, Sugimoto, Y, Kawato, H, Okayama, T, Soga, T. Deposit date: 2013-02-12 Release date: 2013-06-05 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Synthesis and evaluation of novel orally active p53-MDM2 interaction inhibitors Bioorg.Med.Chem., 21, 2013
创建时间：
2013-02-12
