S. aureus dihydrofoate reductase co-crystallized with 3,5-dimethylphenyl-dihydropthalazine inhibitor and NADP(H)
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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S. aureus dihydrofoate reductase co-crystallized with 3,5-dimethylphenyl-dihydropthalazine inhibitor and NADP(H) Descriptor: (2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(3,5-dimethylphenyl)phthalazin-2(1H)-yl]prop-2-en-1-one, Dihydrofolate reductase, GLYCEROL, ... Authors: Bourne, C.R, Thomas, L.M. Deposit date: 2019-07-10 Release date: 2020-06-17 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Inhibitor design to target a unique feature in the folate pocket of Staphylococcus aureus dihydrofolate reductase. Eur.J.Med.Chem., 200, 2020
创建时间：
2019-07-10
