Intrinsically disordered tail of eukaryotic initiation factor 2A binds tRNA and small ribosomal subunit to mitigate stress conditions
收藏资源简介:
This dataset contains molecular dynamics (MD) simulation topology, coordinate, input, and trajectory files accompanying a manuscript currently under peer review titled "Intrinsically disordered tail of eukaryotic initiation factor 2A binds tRNA and small ribosomal subunit to mitigate stress conditions". The files investigate the structural dynamics and predicted molecular interactions between the intrinsically disordered region (IDR) of eIF2A and tRNAi under stress conditions. The repository includes starting coordinate files (Input_IDR_tRNAi.pdb and Input_IDR_tRNAi.gro), the system topology file (topol.top) containing force field definitions, GROMACS parameter input and output log files (MD.mdp and mdout.mdp), and the portable binary run input file (md.tpr). It also features the periodic boundary condition corrected trajectory file sampled at every 50th frame (Output_PBC_corrected_every50th.xtc). All simulations were performed using GROMACS. Full citation details and the manuscript DOI will be updated upon publication.



