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Saccharomyces cerevisiae 3' poly(A) site mapping

Alliance of Genome Resources2026-08-01 收录

替代多聚腺苷酸化位点分析

mRNA转录后调控

数据链接：

https://www.yeastgenome.org/dataset/GSE40110 数据链接链接失效反馈

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资源简介：

The use of alternative polyadenylation sites is common and affects the post-transcriptional fate of mRNA, including its stability, localization, and translation

应用场景：

癌症靶向治疗

mRNA转录后调控

Cleavage by the endonuclease CPSF73 and polyadenylation of nascent RNA is an essential step in co-transcriptional mRNA maturation, and abnormal poly(A) site choices have been associated with human dis

NIAID Data Ecosystem40

Crystal Structure of the C-terminal Domain of CREPT

蛋白质晶体

mRNA转录后调控

Crystal Structure of the C-terminal Domain of CREPT Descriptor: Regulation of nuclear pre-mRNA domain-containing protein 1B Authors: Mei, K, Jin, Z, Ren, F, Wang, Y. Deposit date: 2013-10-22 Release d

Protein Data Bank Japan2024-03-20 更新30

Enterovirus 71 3C Protease Cleaves a Novel Target CstF-64 and Inhibits Cellular Polyadenylation

病毒-宿主相互作用

mRNA转录后调控

Identification of novel cellular proteins as substrates to viral proteases would provide a new insight into the mechanism of cell–virus interplay. Eight nuclear proteins as potential targets for enter

NIAID Data Ecosystem30

CID of human RPRD1B

蛋白质结构解析

mRNA转录后调控

CID of human RPRD1B Descriptor: Regulation of nuclear pre-mRNA domain-containing protein 1B, SULFATE ION, UNKNOWN ATOM OR ION Authors: Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Boun

Protein Data Bank Japan2023-09-20 更新40

ZFP36L1 Negatively Regulates Plasmacytoid Differentiation of BCL1 Cells by Targeting BLIMP1 mRNA

细胞分化调控

mRNA转录后调控

The ZFP36/Tis11 family of zinc-finger proteins regulate cellular processes by binding to adenine uridine rich elements in the 3′ untranslated regions of various mRNAs and promoting their degradation.

NIAID Data Ecosystem30

Saccharomyces cerevisiae 3' poly(A) site mapping

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