SARS-CoV-2 Main Protease (Mpro) in complex with nirmatrelvir alkyne
收藏Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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SARS-CoV-2 Main Protease (Mpro) in complex with nirmatrelvir alkyne Descriptor: 3C-like proteinase nsp5, Nirmatrelvir (reacted form) Authors: Owen, C.D, Crawshaw, A.D, Warren, A.J, Trincao, J, Zhao, Y, Brewitz, L, Malla, T.R, Salah, E, Petra, L, Strain-Damerell, C, Schofield, C.J, Walsh, M.A. Deposit date: 2022-09-14 Release date: 2023-02-22 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.893 Å) Cite: Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. J.Med.Chem., 66, 2023
创建时间:
2022-09-14



