E166A/R274N/R276N Toho-1 Beta-lactamase aztreonam acyl-enzyme intermediate
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E166A/R274N/R276N Toho-1 Beta-lactamase aztreonam acyl-enzyme intermediate Descriptor: 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid, Beta-lactamase Toho-1 Authors: Vandavasi, V.G, Langan, P.S, Weiss, K, Parks, J.M, Cooper, J.B, Ginell, S.L, Coates, L. Deposit date: 2016-07-08 Release date: 2016-11-09 Last modified: 2024-10-09 Method: NEUTRON DIFFRACTION (2.1 Å) Cite: Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A beta-Lactamase with a Monobactam Substrate. Antimicrob. Agents Chemother., 61, 2017
创建时间：
2016-07-08
