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Genome-wide CRISPR/Cas9 Screens Reveal Shared and Bespoke Mechanisms of Resistance to SHP2 inhibition [CRISPR genomic screen]

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP409024
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资源简介:
CRISPR/Cas9 screens identified unexpected hits in human AML cell lines whose loss of function causes resistance to SHP2 inhibition Overall design: CRISPR/Cas9 screens in two human AML cell lines (MOLM13 and MV4-11) to identify resistant hits to SHP2 inhibitor (SHP099)
创建时间:
2023-02-20
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