Monoamine GPCRs

G protein–coupled receptors (GPCRs) which are also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Source: [https://en.wikipedia.org/wiki/G_protein–coupled_receptor Wikipedia] Monoamine GPCRs are Rhodopsin-like GPCRs that bind to monoamine neurotransmitters. [https://en.wikipedia.org/wiki/Monoamine_neurotransmitter Monoamine neurotransmitters]

G蛋白偶联受体（G protein–coupled receptors，简称GPCRs），亦称七次跨膜结构受体、7TM受体、七螺旋受体、蛇形受体及G蛋白连接受体（GPLR），构成一大类蛋白质家族，此类受体可检测细胞外的分子，并激活内部信号转导途径，最终引发细胞反应。与G蛋白的结合使其成为七次跨膜受体，因为它们穿过细胞膜七次。资料来源：[https://en.wikipedia.org/wiki/G_protein–coupled_receptor Wikipedia]。单胺GPCRs属于视紫红质样GPCRs，能够结合单胺神经递质。[https://en.wikipedia.org/wiki/Monoamine_neurotransmitter Monoamine neurotransmitters]