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Whole-genome sequencing to assess off-target effects of SNIP-R

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP681310
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The purpose of the whole-genome sequencing was to assess the potential off-target mutations in SNIP-R genomic deletion platform. SNIP-R mediated deletion of IFNG promoter (or non-targeting control) were performed in activated CD8+ T cells (from two human PBMC donors) and genomic DNA was sent to Genewiz for 10X coverage whole-genome sequencing.
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2026-03-08
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