five

Drosophila intestinal stem

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NIAID Data Ecosystem2026-03-14 收录
下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA934770
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资源简介:
Balancing maintenance of self-renewal and differentiation is a key property of adult stem cells. The epigenetic mechanisms controlling this balance remain largely unknown. Herein, we report that the Polycomb Repressive Complex 2 (PRC2) is required for maintenance of the intestinal stem cell (ISC) pool in adult Drosophila. To identify direct targets of E(z)/PRC2 in ISCs/EBs we conducted genome-wide mapping of chromatin-bound H3K27me3 using ChIP-sequencing.
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2023-02-14
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