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Total Synthesis of Dictyodendrins B and E

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Figshare2016-02-19 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Total_Synthesis_of_Dictyodendrins_B_and_E/2407960
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The concise synthesis of the novel telomerase inhibitors dictyodendrins B and E was completed in only 9 and 11 steps (longest linear sequence). The highly convergent strategy employed a palladium-catalyzed Larock indole synthesis and a palladium-mediated one-pot consecutive Buchwald–Hartwig amination/C–H activation reaction as key steps. The present synthesis exhibits respectable levels of atom-, redox-, and step-economy.
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2016-02-19
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