RNA2Immune

Here, we describe a comprehensive database, RNA2Immune, which aims to provide a high-quality resource of experimentally supported associations linking ncRNA regulatory mechanisms to immune cell function, immune disease, cancer immunology, and vaccines. The current version of RNA2Immune documents 50,433 immune−ncRNA associations in 42 host species, including: (i) 6690 ncRNA associations with immune functions involving 31 immune cell types; (ii) 38,672 ncRNA associations with 348 immune diseases; (iii) 4833 ncRNA associations with cancer immunology; and (iv) 238 ncRNA associations with vaccine responses involving 26 vaccine types targeting 22 diseases.本文介绍一款综合性数据库RNA2Immune，其旨在构建经实验验证的高质量关联资源库，用于建立非编码RNA（non-coding RNA）调控机制与免疫细胞功能、免疫疾病、肿瘤免疫学及疫苗应答之间的关联。当前版本的RNA2Immune共收录了42种宿主物种中的50433条免疫相关非编码RNA关联数据，具体涵盖以下四类：(1) 涉及31种免疫细胞类型的免疫功能相关非编码RNA关联，共计6690条；(2) 与348种免疫疾病相关的非编码RNA关联，共计38672条；(3) 肿瘤免疫学相关非编码RNA关联，共计4833条；(4) 涉及针对22种疾病的26种疫苗类型的疫苗应答相关非编码RNA关联，共计238条。

搜集汇总

背景与挑战

背景概述

RNA2Immune是一个手动管理的数据资源库，专注于整合非编码RNA与免疫调控之间的实验支持关联，涵盖免疫功能、免疫疾病、癌症免疫学和疫苗响应四大领域。该数据库当前版本收录了42个宿主物种中的50,433条关联条目，提供了针对这些领域的浏览和搜索服务。