KCP SHP2i + ERKi
收藏NIAID Data Ecosystem2026-03-14 收录
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KRAS mutant pancreatic tumors have poor prognosis and few therapeutic options. Here, Frank et al. show that the combination of RMC4550 (SHP2 inhibitor) and LY3214996 (ERK inhibitor) effectively impairs tumor growth and induces tumor regression in multiplein vivo models of PDAC . Comparative gene expression profiling analysis of RNA-seq data for KCP tumors treated with vehicle orwith Ly3214996 plus RMC-4550 at 3 weeks
创建时间：
2023-02-23
