G4IPDB

Nucleic acid G-quadruplex structure (G4) Interacting Proteins DataBase (G4IPDB) is an important database that contains detailed information about proteins interacting with nucleic acids that forms G-quadruplex structures. G4IPDB is the first database that provides comprehensive information about this interaction at a single platform. This database contains more than 200 entries with details of interaction such as interacting protein name and their synonyms, their UniProt-ID, source organism, target name and its sequences, ∆Tm, binding/dissociation constants, protein gene name, protein FASTA sequence, interacting residue in protein, related PDB entries, interaction ID, graphical view, PMID, author’s name and techniques that were used to detect their interactions. G4IPDB also provides an efficient web-based “G-quadruplex predictor tool” that searches putative G-quadruplex forming sequences simultaneously in both sense and anti-sense strands of the query nucleotide sequence and provides the predicted G score.

核酸G-四链体结构（G-quadruplex, G4）相互作用蛋白质数据库（G4IPDB）是一款重要的数据库，收录了与可形成G-四链体结构的核酸存在相互作用的蛋白质的详细信息。G4IPDB是首个在单一平台上提供此类相互作用全面信息的数据库。该数据库收录了200余条条目，涵盖相互作用相关的详细信息，包括相互作用蛋白质名称及其同义词、UniProt-ID、源生物体、靶标名称及其序列、∆Tm、结合/解离常数、蛋白质基因名称、蛋白质FASTA序列、蛋白质中的相互作用残基、相关PDB条目、相互作用ID、可视化图形、PMID、作者姓名以及用于检测该相互作用的实验技术。G4IPDB还提供了一款高效的基于网页的"G-四链体预测工具"，可同时在查询核苷酸序列的有义链与反义链中搜索潜在的G-四链体形成序列，并输出预测所得的G评分。