The measurement and determinants of adolescent metabolic syndrome in Africa: a scoping review protocol.

Introduction: Metabolic syndrome (MetS) is a clustering of three to five specific non-communicable diseases that greatly increases an individual’s risk for diabetes and cardiovascular disease. Although previously labelled as a disease afflicting older persons, evidence indicated that younger people were increasingly affected. Hence, countries have studied the disease in younger populations, but research is still lacking in lower- to middle-income countries (LMICs), particularly on the African continent. A scoping review will be conducted to document research that investigated adolescent MetS in Africa, the criteria used to measure this disease in African adolescents, the reported prevalence and extent, as well as the sociodemographic, behavioural, psychosocial, and environmental determinants of adolescent MetS in Africa.
Methods and analysis: The protocol for the proposed scoping review was guided by the high-level steps originally outlined by Arksey and O’Malley, and the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) checklist. We will search and screen descriptive studies published from 1 January 2001 to 28 February 2023. We will use keywords and medical subject headings (MeSH) terms to search electronic databases. Two researchers will screen identified peer-reviewed and grey literature independently, select articles using the inclusion criteria, chart the data, describe the quantitative characteristics of the literature, perform qualitative content analysis, and report the findings.
Ethics and dissemination: We do not require ethics approval as we are reviewing published literature. The results of the scoping review will form part of a Ph.D. thesis submitted to the University of the Western Cape and will be published in a peer-reviewed journal.

引言：代谢综合征（MetS）是一种由三种至五种特定非传染性疾病组成的聚集体，极大地增加了个体患糖尿病和心血管疾病的风险。尽管过去被标记为影响老年人的疾病，但证据表明年轻人受到的影响日益增加。因此，各国开始研究年轻人群中的该疾病，但在中低收入国家（LMICs），尤其是在非洲大陆，相关研究仍显不足。本研究将进行一项范围综述，以记录针对非洲青少年代谢综合征的研究，非洲青少年中测量此疾病的指标，以及该疾病的报告流行率和范围，以及非洲青少年代谢综合征的社会人口学、行为、心理社会和环境决定因素。方法与分析：所提议的范围综述方案遵循了Arksey和O’Malley最初概述的高级别步骤，以及系统综述和荟萃分析扩展范围综述（PRISMA-ScR）清单。我们将搜索和筛选从2001年1月1日至2023年2月28日发表的描述性研究。我们将使用关键词和医学主题词（MeSH）进行电子数据库的搜索。两位研究人员将独立筛选已识别的同行评审和灰色文献，根据纳入标准选择文章，绘制数据，描述文献的定量特征，进行定性内容分析，并报告发现。伦理与传播：由于我们正在审查已发表的文献，因此无需伦理审批。范围综述的结果将构成提交给开普敦大学博士论文的一部分，并将发表在同行评审期刊上。