Supplemental Material:A Case of Delayed-Onset Postoperative Pyoderma Gangrenosum Complicated with Chronic Myelomonocytic Leukemia Treated with Spesolimab
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This dataset contains clinical data from a 63-year-old male patient who developed delayed-onset pyoderma gangrenosum (PG) following laparoscopic inguinal hernia repair and was subsequently diagnosed with chronic myelomonocytic leukemia (CMML). The dataset documents the patient's clinical presentation, laboratory findings, histopathological images, a detailed therapeutic timeline (including antibiotics, corticosteroids, and the IL-36 receptor monoclonal antibody spesolimab), and comparative wound images before and after treatment. This case illustrates the potential role of the IL-36 pathway in the pathogenesis of PG associated with CMML and demonstrates the therapeutic outcome of targeted intervention.



