RETREG1
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=1601869
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资源简介：
The protein encoded by this gene is a cis-Golgi transmembrane protein that may be necessary for the long-term survival of nociceptive and autonomic ganglion neurons. Mutations in this gene are a cause of hereditary sensory and autonomic neuropathy type IIB (HSAN IIB), and this gene may also play a role in susceptibility to vascular dementia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
该基因编码的蛋白质为一种顺式高尔基体跨膜蛋白，该蛋白可能对于痛觉和自主神经节神经元的长期存活至关重要。该基因的突变是遗传性感觉和自主神经病II型（HSAN IIB）的病因之一，并且该基因可能在血管性痴呆的易感性中发挥作用。对于该基因，已观察到存在可进行选择性剪接的转录变体，这些变体编码多种异构体。[由 RefSeq 提供，2011年11月]
提供机构：
Rat Genome Database
