Nucleophosmin (NPM1) is a ubiquitously expressed nucleolar protein with a wide range of functions including ribosome biogenesis, mRNA processing, and maintenance of genomic stability1-4. In acute myel

NIAID Data Ecosystem50

Multi-omics analysis of longitudinal patient samples reveals the molecular mechanism of AML progression [ATAC-seq]. Multi-omics analysis of longitudinal patient samples reveals the molecular mechanism of AML progression [ATAC-seq]

急性髓系白血病分子特征

多组学疾病分析

Relapse remains a determinant of treatment failure and contributes significantly to mortality in acute myeloid leukemia (AML) patients. Despite efforts to understand AML progression and relapse mechan

NIAID Data Ecosystem20

Gene expression analysis of WT and Flt3-ITD multipotent progenitors. Mus musculus

急性髓系白血病分子特征

细胞分化调控

FLT3-ITDs Introduce a Myeloid Differentiation and Transformation Bias in Lympho-myeloid Multipotent Progenitors Overall design: WT multipotent progenitors were compared with FLT3-ITD multipotent proge

NIAID Data Ecosystem70

Novel insights into human respiratory syncytial virus-host factor interactions through integrated proteomics and transcriptomics analysis

病毒-宿主相互作用

药物重定位

The lack of vaccine and limited antiviral options against respiratory syncytial virus (RSV) highlights the need for novel therapeutic strategies. One alternative is to develop drugs that target host f

NIAID Data Ecosystem50

MOESM1 of Repositioning of bromocriptine for treatment of acute myeloid leukemia

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