Transcriptomic analysis of the developing cerebellum in a mouse model for SRD5A3-CDG

We generated Srd5a3 cKO mouse in the cerebellum. To analyze the impact of the genetic defect in the mouse transcriptome, we extracted the RNA from the P7 cerebellum in 4 control and 4 mutant mice, from three different litters.我们构建了小脑特异性Srd5a3条件性敲除（Srd5a3 cKO）小鼠。为分析该遗传缺陷对小鼠转录组的影响，我们从3窝不同产仔的4只野生型对照小鼠与4只突变型小鼠的出生后第7天（P7）小脑中提取了RNA。