Library of libraries: approach to synthetic combinatorial library design and screening of "pharmacophore" motifs.
收藏PubMed Central1995-06-06 更新2026-05-02 收录
下载链接：
https://pmc.ncbi.nlm.nih.gov/articles/PMC41707/
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资源简介：
Construction of synthetic combinatorial libraries is described that allows for the generation of a library of motifs rather than a library of compounds. Peptide libraries based on this strategy were synthesized and screened with model targets streptavidin and anti-beta-endorphin antibody. The screens resulted in observation of expected motifs providing evidence of the effectiveness of the suggested approach.
提供机构：
National Academy of Sciences
创建时间：
1995-06-06
