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Additional file 3 of Integrative blood-derived epigenetic and transcriptomic analysis reveals the potential regulatory role of DNA methylation in ankylosing spondylitis

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DataCite Commons2024-02-08 更新2024-07-29 收录
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https://springernature.figshare.com/articles/dataset/Additional_file_3_of_Integrative_blood-derived_epigenetic_and_transcriptomic_analysis_reveals_the_potential_regulatory_role_of_DNA_methylation_in_ankylosing_spondylitis/17913003/1
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Additional file 3: Supplementary Data S1. 4794 differentially methylated positions (DMPs) identified associated with ankylosing spondylitis in the discovery cohort. Supplementary Data S2. 1,048 differentially variable positions (DVPs) identified with iEVORA algorithm in the discovery cohort. Supplementary Data S3. 4,144 differentially expressed genes (DEGs) identified associated with ankylosing spondylitis in the discovery cohort. Supplementary Data S4. 158 differentially methylated positions (DMPs) identified to be correlated with the corresponding mRNA expression levels of 112 genes in Pearson correlation analyses. Supplementary Data S5. The differentially methylated positions (DMPs) of 6 key genes identified in the Pearson correlation analyses were verified in the validation cohort.
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2022-01-06
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