Associations between IgG responses and anti-disease/anti-parasite immunity.

*The effect of malariometric status on IgG responses (IgGt: total IgG), determined by ANCOVA, was adjusted for age.**Significantly different after adjustment for multiple tests (Bonferroni correction, threshold of significance: P = 0.002).***Logistic regression was applied for the analysis of associations with protection against malaria attacks, where status (UMA vs ACLP groups) was used as the dependent variable against the explanatory variables (IgG subtype responses (IgG3 to MSP2 FC27 and IgG1 to GLURP) and age) shown to be significantly associated by ANCOVA. OR values were assessed for 10 AU increased. Age was also associated with malaria protection in the analysis (p = 0.011, OR = 0.84).