Abstract:Our previous study found that 1-nitropyrene (1-NP) exposure evoked pulmonary fibrosis in mice. However, the exact mechanism remained elusive. We found that 1-NP induced telomere damage and ce

NIAID Data Ecosystem20

Additional file 2: Figures S4-S6. of B cell depletion therapy upregulates Dkk-1 skin expression in patients with systemic sclerosis: association with enhanced resolution of skin fibrosis

系统性硬化症

纤维化分子机制

Dkk-1 is not expressed in epidermis (black arrow), appendices (green arrow) and spindle-like cells (red arrows) prior to (A and B) and following RTX treatment (D and E). These patients did not respond

NIAID Data Ecosystem20

Oncopig Liver Cirrhosis sequencing Datasets

纤维化分子机制

非酒精性脂肪肝转录组学

Transcriptional (RNA-seq) profiling of Oncopig liver fibrosis and age-matched normal control liver samples collected 8-weeks post induction of alcoholic liver disease.

NIAID Data Ecosystem50

Data_Sheet_2_ADAMTS8 Promotes Cardiac Fibrosis Partly Through Activating EGFR Dependent Pathway.ZIP

纤维化分子机制

Myocardial infarction or pressure overload leads to cardiac fibrosis, the leading cause of heart failure. ADAMTS8 (A disintegrin and metalloproteinase with thrombospondin motifs 8) has been reported t

NIAID Data Ecosystem20

Differential expression of redox regulating proteins in cultured CF epithelia.

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