Expression data from NRF3 knockdown or overexpression cells. Expression data from NRF3 knockdown or overexpression cells

The genetic association of a transcription factor NRF3 with obesity has been reported, although the molecular mechanisms remain unknown We used microarrays to identify NRF3-regulated gene expression network related to lipid metabolism. Overall design: For RNA extraction and hybridization on Affymetrix microarrays, we prepated HCT116 cells transciently transfected NRF3 or control siRNA, p53-deficient HCT116 (HCT116-p53KO) cells transciently transfected NRF3 or control siRNA, and H1299 cells stably expressing NRF3 or GFP.