five

Mus musculus strain:C57BL/6 Raw sequence reads

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https://www.ncbi.nlm.nih.gov/sra/SRP219766
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TLR2 is expressed on the cell surface of activated and memory CD4+ and CD8+ T cells. Therefore, activation of TLR2 directly enhances TCR signal-induced T cell activation, function, and survival, serving as a co-stimulatory molecule. To study the mechanisms of P3C-induced CD8+ T cell activation, we compared the transcriptional signature of CD8+ T cells after anti-CD3, P3C, or combined stimulation and analyzed differentially expressed genes (DEGs) between naïve and activated CD8+ T cells.
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2020-05-20
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