EGFR kinase domain T790M/L858R mutant with HKI-272
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3w2q
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EGFR kinase domain T790M/L858R mutant with HKI-272 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor, N-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)butanamide Authors: Sogabe, S, Kawakita, Y, Igaki, S. Deposit date: 2012-12-03 Release date: 2013-01-16 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure-Based Approach for the Discovery of Pyrrolo[3,2-d]pyrimidine-Based EGFR T790M/L858R Mutant Inhibitors. Acs Med.Chem.Lett., 4, 2013
创建时间：
2012-12-03
