Genome-wide significant associations (p<5×10<sup>−8</sup>) at novel loci in analysis of age-adjusted and full-plus-triglycerides-adjusted<sup>*</sup> lipoprotein fractions.
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*Full adjustment procedure (age, BMI, smoking status, menopausal status, use of hormone replacement therapy; see Materials and Methods) with addition of log-transformed triglyceride levels. +Most significant association among LDL-C, HDL-C, and triglycerides (TG) in recent meta-analysis [10]. n.s. = not significant (P>0.05). #Abbreviation as in Table 2. ∧P-value (two-sided) for association in additional 4639 samples from the WGHS. All association trends were consistent with discovery sample. Combining these new samples with the original discovery samples leads to p–values for the extended WGHS sample.
创建时间:
2009-11-20



