Usp16 deletion-induced gene expression in MEFs
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https://www.ncbi.nlm.nih.gov/sra/SRP290124
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To determine the molecular signaling pathways responsible for USP16 regulation of cell growth, RNA sequencing was conducted on MEFs with or without Usp16 deletion Overall design: SV40T-immortalized K-rasG12D/Usp16+/+ and K-rasG12D/Usp16flox/flox MEFs were infection with Ad-Cre to activate K-rasG12D expression and delete the floxed Usp16 alleles. These cells denoted by K-rasG12D;Usp16+/+/SV40T (KS) and K-rasG12D;Usp16-/-/SV40T (UKS). The gene expression profiling in the MEFs with or without Usp16 deletion were analyzed by RNA-seq.
创建时间：
2021-07-22
