Comparing mRNA expression of Myc/NrasG12V and Myc/Akt1 driven liver tumors
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资源简介：
To analyze mRNA expression of Myc/NrasG12V and Myc/Akt1 driven liver tumors (HCC), we generated HCCs with elevated MYC expression and activated Raf-MEK-ERK or Akt1 signaling. To trigger tumor development, we co-delivered transposable elements encoding for Myc and oncogenic NrasG12V or myristoylated Akt1 via hydrodynamic injection into the hepatocytes of C57BL/6 wildtype mice and analyzed the transcriptomes of the developed tumors. mRNA expression of Myc/NrasG12V and Myc/Akt1 driven liver tumors was compared via mRNAseq analysis
创建时间：
2020-12-04
